Biomarkers in FemTech
The term “biomarker,” a short version of “biological marker,” refers to a broad subcategory of medical signs. Biomarkers represent a considerable part of precision medicine. Biomarkers can be classified based on different parameters, including their characteristics, such as imaging biomarkers (computed tomography, positron emission tomography, magnetic resonance imaging) or molecular biomarkers.
Biomarker sets depend on the purpose, health state, sex and age. Gender differences inﬂuence health (and, consequently, the necessary biomarkers set) in a variety of ways:
Biological differences, such as, genes, hormones, and different morbidity risks
Acquired risks, such as, risk of disease and risk of accidents in the workplace, due to free-time activities, lifestyle, psychological distress, and social environment
Psychological aspects of symptoms and treatment including how symptoms are perceived and rated in terms of severity, as well as reaching a decision and implementation of treatment
From a biological point of view, reproductive aging (r-Aging) is essential in women. Female reproductive aging is, in a way, a biological phenomenon that develops along canonical molecular pathways; however, it has particular features. It was shown that reproductive aging has complex connections with the aging of other systems (somatic aging) and can impact aging processes in an organism at multiple levels (cells, tissues, organs, and systems).
Biomarkers and FemTech
Female Biomarkers in Longevity
The aging process leads to the loss of functions in several physiological systems, which are often accompanied by age-related diseases. Biomarkers of aging are tools used to provide a quantitative foundation to estimate the overall health status and the therapeutic efficacy of clinical, healthspan-extending interventions.
Female biomarkers provide specific information about functional activity and the overall health status of only female organisms. Thus, detecting and analyzing female biomarkers enables a personalized approach in the aging-related field. Nowadays, many aging biomarkers define not only a restricted set of physiological functionalities whose disruptions are known to trigger the onset of specific aging-related disorders. Furthermore, the following female biomarkers can be linked with Longevity: biomarkers of female cancer as one of the leading causes of mortality (breast, ovarian, cervical, endometrial cancer), reproductive health biomarkers as the indicator of population aging. And finally, biomarkers of general women’s health.
Source: Ageing Research Reviews